MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism
نویسندگان
چکیده
منابع مشابه
Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring.
Maternal consumption of a high-fat diet (HFD) during pregnancy and lactation is closely related to hepatic lipid accumulation, insulin resistance and increased serum cytokine levels in offspring and into their adulthood. MicroRNA (miRNA) have been implicated in cholesterol biosynthesis and fatty acid metabolism. We evaluated the modulation of hepatic fatty acid synthesis (de novo), β-oxidation ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2010
ISSN: 0022-2275
DOI: 10.1194/jlr.m004812